A rare neurological presentation of celiac disease

Background: Celiac disease (CD) is an autoimmune disease of the small intestine due to sensitivity to gluten, a protein which is present in wheat, rye, and barley. Th e most common clinical fi ndings in CD are gastrointestinal complications but neurological presentations are also seen in some patients. Case report: A case is described of a 40-year-old man who presented CD-related optic neuropathy, a very rare neurological manifestation of CD. He reported sudden right upper visual fi eld blindness upon awakening in the morning without pain. He was treated with intravenous methylprednisolone for fi ve days, followed by two-year azathioprine and methotrexate administration. His case is presented with magnetic resonance imaging, clinical history, and laboratory fi ndings. Conclusion: It is reasonable that CD patients be evaluated for neurological symptoms even in the clinically stable long-term course. In addition, CD needs to be considered when making a diff erential diagnosis for patients presenting neurological symptoms of unknown